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KMID : 0378019680110120049
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New Medical Journal
1968 Volume.11 No. 12 p.49 ~ p.59
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Effect of Epinephrine and Prednisolone on Arthus Reaction
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Abstract
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The author investigated, using rabbits, the effect of epinephrine and prednisolone on Arthus reaction. The animals were sensitized by repeated, intravenous or intraperitoneal injections of egg-albumin over a period of 4 or 5 Nveeks. The highly sensitized animals then were injected intradermally with the mixture of egg-albmin and epinephrine or prednisolone or egg-albumin alone within a few hours following a single systemic administration of epinephrine or prednisolone.
The results thus obtained were discussed and the conclusions drawn therefrom axe as follows:
1. The Arthus reaction was_intensified by the local or systemic administration of epinephrine.
2. The Arthus reaction was depressed by the local or systemic administration of prednisolone.
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